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overall lab publication & PDF library
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Jennifer H. Cox, Amanda E. Starr, Reinhild Kappelhoff, Rendi Yan, Clive R. Roberts, Christopher M. Overall Matrix metalloproteinase 8 deficiency in mice exacerbates inflammatory arthritis through delayed neutrophil apoptosis and reduced caspase 11 expression Arthritis & Rheumatism Vol. 62, No. 12, December 2010, pp 3645-3655 [PDF] [Supplementary Figures] |
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Charlotte J. Morrison, Georgina S. Butler, David Rodriguez and Christopher M. Overall Matrix Metalloproteinase Proteomics: Substrates, Targets and Therapy Curr Opin Cell Biol. 2009 Jul 16 [PDF] |
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Ulrich auf dem Keller, Alain Doucet, and Christoph M. Overall Protease research in the era of systems Biology Biol. Chem. 388, 1159-62 (2007) [PDF] |
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Christopher M. Overall, and Georgina S. Butler Protease Yoga: Extreme Flexibility of a Matrix Metalloproteinase Structure 15, 1159-61 (2007) [PDF] |
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Richard A. Dean, Georgina S. Butler, Yamina Hamma-Kourball, Jean Delbe, David R. Brigstock, Jose Courty, and Christopher M. Overall Identification of novel MMP2 substrates by ICAT quantitative proteomics Mol. Cell. Biol., advanced online publication (2007) [PDF] |
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Christopher M. Overall , Oded Kleifeld Validating Matrix Metalloproteinases as Drug Targets and Anti-targets for Cancer Therapy Nature Reviews Cancer 6, 227-239 (2006) [PDF] |
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Christopher M. Overall and Richard Dean Degradomics: Systems Biology of the Protease Web. Pleiotropic Roles of MMPs in Cancer Cancer Metastasis Reviews 25, 69-75 [PDF] |
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Christopher M. Overall and Oded Kleifeld Towards Third Generation Matrix Metalloproteinase Inhibitors for Cancer Therapy British Journal of Cancer 94, 941-946. [PDF] |
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Gayle R. Pelman, Charlotte, J. Morrison, Christopher M. Overall Pivotal Molecular Determinants of Peptidic and Collagen Triple Helicase Activities Reside in the S3' Subsite of Matrix Metalloproteinase 8 (MMP 8): THE ROLE OF HYDROGEN BONDING POTENTIAL OF ASN188 AND TYR189 AND THE CONNECTING CIS BOND J. Biol. Chem. 280, 2370-2377 (2005) [PDF] |
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Christopher M. Overall Dilating the Degradome: Matrix Metalloproteinase-2 Cuts to the Heart of the Matter Biochemical Journal 383 (3), e5-e7 (2004). Invited commentary [PDF] Mounted on the Internet with the permission of The Biochemical Society 2004 |
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