www.clip.ubc.ca
Looking South down Howe Sound towards Anvil Island and Keats Island. The Overall Lab is at UBC located 8 km to the south east

 Hmmm... nice new lab!


The University of British Columbia
Department of Oral Biological & Medical Sciences
Department of Biochemistry & Molecular Biology

Affiliations
CIHR Group in Matrix Dynamics
The UBC Centre for Blood Research
The UBC Centre for Prostate Research


Member of
The Canadian Protein Engineering Network
Canadian Proteomics Network
British Columbian Proteomics Network
Canadian Arthritis Network of Centres of Excellence
chris overall, overall lab, UBC, Vancouver, BC, Canada

MMP, TIMP, MT-MMP, gelatinase, protease, proteinase, enzyme, marimastat, hemopexin, exosite, domain, chemokine, MCP, SDF
UBC Crest
collagenase, proteomics, degradomics, CAN, PENCE, gordon, conference, GRC, exosite, metallo, enzyme

A proteomics and protein engineering research laboratory with specialized interest in Degradomics of the Protease Web.
We focus on developing new quantitative proteomic techniques to identify and understand the protease degradome (specifically the Matrix Metalloproteinases (MMPs) and their inhibitors, TIMPs, and the deubiquitinylating proteases, DUBs), and their substrates, the substrate degradome, in normal cells and in disease. Therefore we have active research projects in the cancer degradome, in the role of MMPs in controlling the chemokine web and innate immunity, and in HIV infection.

 

  

The Overall Lab The Overall Lab... overlooking the car park! The Overall Lab... overlooking the car park! Cypress Mountain Ski Bowl, 60 min from the bench Point Atkinson Light House Bowen Island Gambier Island Howe Sound Tantalus Icefield Site of the new Overall Lab in the UBC Life Sciences Building October 2004... overlooking another car park Peter Wall Institute Whistler Blackcomb Mountain:  North America's No. 1 Rated Ski Resort, 80 min from here UBC Swimming Centre Woodward Medical Library War Memorial Gym Keats Island, snug behind Mount Gardner on Bowen Island Burrard Inlet Burrard Inlet Howe Sound The Overall Lab Home Page The Overall Lab... overlooking the car park! The Overall Lab... overlooking the car park! The Overall Lab... overlooking the car park! The Overall Lab... overlooking the car park!

Resources
TopFIND - the protein termini and protease substrate database | WebPICS - Proteomic Identification of protease Cleavage Sites